منابع مشابه
Retrograde axonal tracing with fluorescent markers.
The growth of fluorescence imaging technology and the development of sensitive fluorescent retrograde tracers has provided many new approaches for analyzing neuronal circuits. Fluorescent markers provide unparalleled opportunity for combining axonal tract tracing with techniques such as immunohistochemistry or physiological recording. This unit describes the use of six different fluorescent tra...
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Retrograde transport, in which proteins and lipids are shuttled between endosomes and biosynthetic/secretory compartments such as the Golgi apparatus, is crucial for a diverse range of cellular functions. Mechanistic studies that explore the molecular machinery involved in this retrograde trafficking route are shedding light on the functions of transport proteins and are providing fresh insight...
متن کاملPlant Intracellular Transport: Tracing Functions of the Retrograde Kinesin
Adding to its varied repertoire of functions in cell morphogenesis and cell division, a molecular motor protein of the kinesin-14 class has recently been implicated in rapid retrograde transport along cellular tracks in moss.
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Most RNA viruses undergo mutations inside the host at an incessant rate that allows them to elude the immune response. This constant evolution in RNA viruses is due to the low fidelity in replication carried out by the virus encoded RNA dependent RNA polymerases. This mis-incorporation of bases leads to establishment of a quasispecies of virus in the host. This makes it a challenge to combat vi...
متن کاملRetrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb.
Identifying the connectome of adult-generated neurons is essential for understanding how the preexisting circuitry is refined by neurogenesis. Changes in the pattern of connectivity are likely to control the differentiation process of newly generated neurons and exert an important influence on their unique capacity to contribute to information processing. Using a monosynaptic rabies virus-based...
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ژورنال
عنوان ژورنال: Science
سال: 2007
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.316.5833.1814c